Kizzire closed with a 3-under 69 to match Kang at 19-under 269 at Thanksgiving Point. The 29-year-old former Auburn player earned $117,000 to push his tour-leading total to $391,699 — giving him a lead of $123,211 over No. 2 Peter Malnati.
"Winning a tournament and winning the money title are the two goals that I have this year," Kizzire said. "To finally get winning the tournament under my belt gives me a solid advantage going into the last four tournaments to secure that top spot."
He won after finishing second this season in the Mexico Championship and Rex Hospital Open.
"I'm pretty relieved and excited," Kizzire said. "It was a big event. I'm glad this is the one I won. The victories seem to be a little sweeter after all the near misses."
Kang had five back-nine birdies in a 67. He tied for second in the event last year in Sandy.
"I played great today, especially on the back nine. I started off pretty good, and then the wind actually gusted really hard in the middle of the round, and I made a couple of mistakes," Kang said. "But on the back nine, I at least got in the playoff."
Kizzire set up his winning putt on the par-4 18th with a wedge shot from 63 yards, after Kang left his 75-yard shot 40 feet short. Kang had birdie chances to win on the final hole of regulation and first playoff hole, but missed 20-foot putts.
Kizzire opened with rounds of 67, 62 and 71 to take a two-stroke lead over Kang into the final day, and had a four-shot advantage midway through the final round.