The result was a pair of right leg injuries for two of the NFL's best players.
Peterson injured his right foot Sunday when he caught a short pass from Matt Cassel, headed to the right sideline and was tackled by Arthur Brown in the second quarter of Minnesota's 29-26 loss at Baltimore.
"I haven't seen the replay, but my foot was extended and kind of got rolled up, kind of like a horse-collar tackle type," said Peterson, who is among the NFL leaders with 1,221 yards rushing. "I just felt it pop a couple times and the pain was excruciating. I came in and tried to tape it up again after getting the X-ray done. I just couldn't do it with the push off."
Peterson is expected to undergo an MRI on Monday. Asked If this could be a season-ending injury, the 2012 NFL MVP said: "Not at all. You should have seen me in here trying to get back out there. I kept my pads on, too, until the third quarter, until I finally was just like, 'I'm not ready to go.'"
It was a much different situation in New England, which lost Gronkowski to a suspected torn anterior cruciate ligament in his right knee during the third quarter of a 27-26 victory over Cleveland.
Gronkowski was hurt on a hit by Browns safety T.J. Ward after a 21-yard reception. Coach Bill Belichick said he was taken to a hospital for evaluation.
"We've sustained some pretty big injuries this year with really important, critical players," Patriots quarterback Tom Brady said. "I think we all feel sorry for Rob, but I don't think anyone feels sorry for the Patriots."
Gronkowski missed the first six games of the season while recovering from offseason forearm and back surgeries. Wide receiver Danny Amendola, running back Shane Vereen and defensive players Vince Wilfork, Jerod Mayo and Tommy Kelly also have missed an extended amount of time for New England.
Vikings tight end John Carlson, tight end Nick Kasa and defensive tackle Vance Walker of the Raiders, and Dolphins running back Lamar Miller all sustained concussions. Falcons safety Thomas DeCoud departed in the first quarter of a 22-21 loss at Green Bay due to a head injury.
Washington running back Evan Royster was carted off the field in the first half of the Redskins' 45-10 loss to Kansas City after he sprained his left ankle. Chiefs cornerback Marcus Cooper departed the same game with a bruised back.
AP NFL website: http://www.pro32.ap.org