The team downgraded Lee from probable to questionable Saturday. Lee missed the entire preseason and the opener with a hamstring injury. He played sparingly last week against Miami, catching two passes for 27 yards and gaining 12 yards on an end-around.
A second-round draft pick in 2014, Lee has 39 career receptions for 422 yards and a touchdown.
In case Lee can't play, the Jaguars (1-1) promoted receiver Tony Washington from the practice squad. To make room for Washington on the 53-man roster, Jacksonville cut linebacker and special teams ace LaRoy Reynolds. Reynolds has played in 30 games, including three starts, in three seasons.