CHICAGO — After a rough start, Chris Sale showed signs of his dominant form, but by then damage was done.
Hunter and Eduardo Nunez tagged Sale (3-2) for solo home runs in the second inning. It was Hunter's seventh of the season and Nunez's first.
"I basically lost the game right there in the second inning, giving up two homers. I just have to be down with it. No matter how hard it is if it's up they're going to take advantage," said Sale.
Sale struggled early but pitched eight innings. He gave up four runs, three earned, and five hits. He struck out 10 and allowed one walk.
"I think early on, they just seemed to be on his fastball. They get those quick homers and they got him early. After that, I think he started mixing it up," said White Sox manager Robin Ventura. "They might have been seeing something, they can sit on some stuff. He threw great after that."
The White Sox have lost four of their last five games and Jose Abreu's 17-game hitting streak ended.
May (3-3) allowed three runs and six hits. He struck out nine and didn't allow a walk.
"I felt pretty comfortable with the changeup today. I was aggressive with it. I wasn't afraid to throw it four, five times in a row. With the shadows, that definitely helps," said May.
Twins closer Glen Perkins pitched a scoreless ninth for his major league-leading 16th save in 16 chances. Perkins struck out Tyler Flowers looking to end the game, leaving runners at first and second.
Adam LaRoche doubled in the second inning and scored on Alexei Ramirez's single.
Sale ran into more problems in the third inning. Shane Robinson's groundout drove in Danny Santana and Trevor Plouffe's RBI single gave the Twins a 4-1 lead.
Twins center fielder Aaron Hicks robbed Eaton of extra bases in the eighth with a diving catch.
"I'm glad to watch somebody that can really play some center field," said Hunter. "It gave me a little flashback from about 12 years ago."
Before the game, the White Sox retired Paul Konerko's No. 14 jersey. Konerko spent 16 seasons with the White Sox. He was honored with a statue last season on the outfield concourse. On Saturday, he returned to see his number retired. He thanked everyone from White Sox chairman Jerry Reinsdorf to his first minor league manager Joe Vavra, who is the current bench coach for the Twins.
Twins starter Kyle Gibson (3-3) is scheduled to start Sunday against the White Sox. In his last outing against the White Sox on May 1st, he pitched eight scoreless innings in a 1-0 victory.
Jose Quintana (2-4) is hoping for run support in his Sunday scheduled start against the Twins. He is 1-3 in his last five starts, but has 2.18 ERA in that span.